Browsing by Author "Hetz Flores, Claudio Andres"

Now showing items 1-4 of 4

    • A phenolic-rich extract from ugni molinae berries reduces abnormal protein aggregation in a cellular model ... 
      Pérez Arancibia, Rodrigo Nicolás; Ordóñez, José Luis; Rivas, Alexis; Pihán, Philippe; Sagredo, Alfredo; Ahumada, Ulises; Barriga, Andrés; Seguel, Ivette; Cárdenas, César; Vidal, René L.; Hetz Flores, Claudio Andres; Delporte Vergara, Carla Luz (Public Library Science, 2021)
      Accumulation of misfolded proteins in the brain is a common hallmark of most age-related neurodegenerative diseases. Previous studies from our group identified the presence of anti-inflammatory and antioxidant compounds ...
    • Neuronal rubicon represses extracellular APP/amyloid beta deposition in Alzheimer's disease 
      Espinoza, Sandra; Grunenwald, Felipe; Gomez, Wileidy; García, Felipe; Abarzúa Catalán, Lorena; Oyarce Pezoa, Sebastián; Hernández, María Fernanda; Cortés, Bastián I.; Uhrig, Markus; Ponce de la Vega, Daniela Paz; Durán Aniotz, Claudia; Hetz Flores, Claudio Andres; San Martín Rovirosa, Carol Dazil; Cornejo Corona, Víctor Hugo; Ezquer, Fernando; Parra Ortiz, Valentina María; Behrens Pellegrino, María Isabel Ofelia; Manque, Patricio A.; Rojas Rivera, Diego; Vidal, René L.; Woehlbier, Ute; Nassif, Melissa (MDPI, 2022)
      Alzheimer's disease (AD) is the most prevalent age-associated neurodegenerative disease. A decrease in autophagy during aging contributes to brain disorders by accumulating potentially toxic substrates in neurons. Rubicon ...
    • Papel pronóstico de la respuesta al mal plegamiento de proteínas en distintos grupos moleculares de ... 
      Fernández Gajardo, Rodrigo (Universidad de Chile, 2021)
      Introducción. El glioblastoma multiforme (GBM) es la neoplasia primaria maligna más frecuente del sistema nervioso central y se caracteriza por ser un tumor altamente heterogéneo desde el punto de vista histopatológico ...
    • Paradoxical implication of BAX/BAK in the persistence of tetraploid cells 
      Deng, Jiayin; Gutiérrez, Lucía; Stoll, Gautier; Motino, Omar; Martins, Isabelle; Núñez, Lucía; Bravo San Pedro, José Manuel; Humeau, Juliette; Bordenave, Chloe; Pan, Juncheng; Fohrer Ting, Helene; Souquere, Sylvie; Pierron, Gerard; Hetz Flores, Claudio Andres; Villalobos, Carlos; Kroemer, Guido; Senovilla, Laura (Springernature, 2021)
      Pro-apoptotic multi-domain proteins of the BCL2 family such as BAX and BAK are well known for their important role in the induction of mitochondrial outer membrane permeabilization (MOMP), which is the rate-limiting step ...